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1

Rafting through traffic: Membrane domains in cellular logistics

Diaz-Rohrer, Blanca, Levental, Kandice R., Levental, Ilya

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

2

Modular StarPEG-Heparin Gels with Bifunctional Peptide Linkers

Mikhail V. Tsurkan, Karolina Chwalek, Kandice R. Levental, Uwe Freudenberg, Carsten Werner

Journal:

Macromolecular Rapid Communications

Year:

2010

Language:

english

File:

PDF, 444 KB

english, 2010

3

FGF-2 and VEGF functionalization of starPEG–heparin hydrogels to modulate biomolecular and physical cues of angiogenesis

Andrea Zieris, Silvana Prokoph, Kandice R. Levental, Petra B. Welzel, Milauscha Grimmer, Uwe Freudenberg, Carsten Werner

Journal:

Year:

2010

Language:

english

File:

PDF, 1.24 MB

english, 2010

4

Using Mean Field Theory to Guide Biofunctional Materials Design

Uwe Freudenberg, Jens-Uwe Sommer, Kandice R. Levental, Petra B. Welzel, Andrea Zieris, Karolina Chwalek, Katja Schneider, Silvana Prokoph, Marina Prewitz, Ron Dockhorn, Carsten Werner

Journal:

Advanced Functional Materials

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

5

Two-tier hydrogel degradation to boost endothelial cell morphogenesis

Karolina Chwalek, Kandice R. Levental, Mikhail V. Tsurkan, Andrea Zieris, Uwe Freudenberg, Carsten Werner

Journal:

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

6

Sustained delivery of SDF-1α from heparin-based hydrogels to attract circulating pro-angiogenic cells

Silvana Prokoph, Emmanouil Chavakis, Kandice R. Levental, Andrea Zieris, Uwe Freudenberg, Stefanie Dimmeler, Carsten Werner

Journal:

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

7

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

Kandice R. Levental, Hongmei Yu, Laura Kass, Johnathon N. Lakins, Mikala Egeblad, Janine T. Erler, Sheri F.T. Fong, Katalin Csiszar, Amato Giaccia, Wolfgang Weninger, Mitsuo Yamauchi, David L. Gasser,

Journal:

Year:

2009

Language:

english

File:

PDF, 3.17 MB

english, 2009

8

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathon N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Hwang, E Shelley, Chen,

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 1.71 MB

english, 2014

9

Perturbation of Plasma Membrane Physical Properties by Endogenous and Exogenous Mediators Affects Cell Function

Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 120 KB

english, 2014

10

Structural Determinants of Protein Association with Membrane Rafts and Consequences of Raft Mislocalization

Levental, Ilya, Levental, Kandice, Diaz-Aguilar, Blanca B.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 41 KB

english, 2014

11

Differentiation of Plasma Membrane Composition and Physical Properties

Levental, Ilya, Levental, Kandice R.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

12

[Current Topics in Membranes] Lipid Domains Volume 75 || Giant Plasma Membrane Vesicles: Models for Understanding Membrane Organization

Levental, Kandice R.

Year:

2015

Language:

english

File:

PDF, 1.71 MB

english, 2015

13

Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds

Freudenberg, Uwe, Zieris, Andrea, Chwalek, Karolina, Tsurkan, Mikhail V., Maitz, Manfred F., Atallah, Passant, Levental, Kandice R., Eming, Sabine A., Werner, Carsten

Journal:

Journal of Controlled Release

Year:

2015

Language:

english

File:

PDF, 2.59 MB

english, 2015

14

Polyunsaturated Lipids Regulate Membrane Domain Stability by Tuning Membrane Order

Levental, Kandice R., Lorent, Joseph H., Lin, Xubo, Skinkle, Allison D., Surma, Michal A., Stockenbojer, Emily A., Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 1.69 MB

english, 2016

15

Order Differences between Coexisting Liquid Phases Driven by Lipid Unsaturation Determine Phase Separation in Biomimetic Membranes

Lin, Xubo, Lorent, Joseph H., Levental, Kandice R., Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 36 KB

english, 2016

16

Dietary Fats Remodel Plasma Membrane Lipidome and Physical Properties to Regulate Phase Separation in Biological Membranes

Levental, Kandice R., Lorent, Joseph H., Lin, Xubo, Gorfe, Alemayehu A., Levental, Ilya

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

17

Structural Determinants of Raft Partitioning for Single-Pass Transmembrane Proteins

Lorent, Joseph H., Diaz-Rohrer, Barbara B., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 39 KB

english, 2016

18

Defined Polymer-Peptide Conjugates to Form Cell-Instructive starPEG-Heparin Matrices In Situ

Tsurkan, Mikhail V., Chwalek, Karolina, Prokoph, Silvana, Zieris, Andrea, Levental, Kandice R., Freudenberg, Uwe, Werner, Carsten

Journal:

Advanced Materials

Year:

2013

Language:

english

File:

PDF, 972 KB

english, 2013

19

Modular GAG-matrices to promote mammary epithelial morphogenesis in vitro

Nowak, Mirko, Freudenberg, Uwe, Tsurkan, Mikhail V., Werner, Carsten, Levental, Kandice R.

Journal:

Year:

2017

Language:

english

File:

PDF, 2.48 MB

english, 2017

20

Domain Stability in Biomimetic Membranes Driven by Lipid Polyunsaturation

Lin, Xubo, Lorent, Joseph Helmuth, Skinkle, Allison D., Levental, Kandice R., Waxham, Melvin Neal, Gorfe, Alemayehu A., Levental, Ilya

Journal:

Journal of Physical Chemistry B

Year:

2016

Language:

english

File:

PDF, 8.27 MB

english, 2016

21

Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival

He, Jingquan, Zhang, Feng, Tay, Li Wei Rachel, Boroda, Salome, Nian, Weiqi, Levental, Kandice R., Levental, Ilya, Harris, Thurl E., Chang, Jeffrey T., Du, Guangwei

Journal:

The FASEB Journal

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

22

Structural determinants and functional consequences of protein affinity for membrane rafts

Lorent, Joseph H., Diaz-Rohrer, Blanca, Lin, Xubo, Spring, Kevin, Gorfe, Alemayehu A., Levental, Kandice R., Levental, Ilya

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 1.70 MB

english, 2017

23

n -Alcohol Length Governs Shift in L o - L d Mixing Temperatures in Synthetic and Cell-Derived Membranes

Cornell, Caitlin E., McCarthy, Nicola L.C., Levental, Kandice R., Levental, Ilya, Brooks, Nicholas J., Keller, Sarah L.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

24

ω-3 polyunsaturated fatty acids direct differentiation of the membrane phenotype in mesenchymal stem cells to potentiate osteogenesis

Levental, Kandice R., Surma, Michal A., Skinkle, Allison D., Lorent, Joseph H., Zhou, Yong, Klose, Christian, Chang, Jeffrey T., Hancock, John F., Levental, Ilya

Journal:

Science Advances

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

25

Sphingomyelin metabolism is a regulator of KRAS function

van der Hoeven, Dharini, Cho, Kwang-jin, Zhou, Yong, Ma, Xiaoping, Chen, Wei, Naji, Ali, Montufar-Solis, Dina, Zuo, Yan, Kovar, Sarah E., Levental, Kandice R., Frost, Jeffrey A, van der Hoeven, Ransom

Journal:

Molecular and Cellular Biology

Year:

2017

Language:

english

File:

PDF, 6.45 MB

english, 2017

26

Author Correction: Structural determinants and functional consequences of protein affinity for membrane rafts

Lorent, Joseph H., Diaz-Rohrer, Blanca, Lin, Xubo, Spring, Kevin, Gorfe, Alemayehu A., Levental, Kandice R., Levental, Ilya

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 287 KB

english, 2018

27

Structural Determinants and Functional Consequences of Protein Association with Membrane Domains

Lorent, Joseph, Diaz-Rohrer, Blanca Barbara, Lin, Xubo, Gorfe, Alex, Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 41 KB

english, 2018

28

Homeostatic Remodeling of Mammalian Membranes in Response to Dietary Lipid Perturbations is Essential for Cellular Fitness

Levental, Kandice R., Malmberg, Eric, Levental, Ilya

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 39 KB

english, 2018

29

Tuning Length Scales of Small Domains in Cell-Derived Membranes and Synthetic Model Membranes

Cornell, Caitlin E., Skinkle, Allison D., He, Shushan, Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 2.52 MB

english, 2018

30

Molecular Mechanism of Microdomain Dependent Protein Trafficking

Diaz-Rohrer, Blanca B., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 40 KB

english, 2018

31

Manipulation of Length Scales in a Modulated Phase in Cell-Derived GPMVs and Synthetic Model GUVs

Cornell, Caitlin E., Skinkle, Allison D., Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 42 KB

english, 2018

32

Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux

Torres-Adorno, Angie M., Vitrac, Heidi, Qi, Yuan, Tan, Lin, Levental, Kandice R., Fan, Yang-Yi, Yang, Peiying, Chapkin, Robert S., Eckhardt, Bedrich L., Ueno, Naoto T.

Journal:

Year:

2018

Language:

english

File:

PDF, 4.04 MB

english, 2018

33

Tuning Length Scales of a Modulated Phase in Model and Cell-Derived Membranes

Cornell, Caitlin E., Skinkle, Allison D., He, Shushan, Levental, Ilya, Levental, Kandice R., Keller, Sarah L.

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 44 KB

english, 2019

34

Phase Partitioning of Peptide Anchors in Plasma Membrane Vesicles Predicts Their Recruitment to B Cell Receptor Clusters in Live Cells

Shelby, Sarah A., Serrano, Ivan C., Levental, Kandice R., Levental, Ilya, Veatch, Sarah L.

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 63 KB

english, 2019

35

Phosphatidylserine (PS) Externalization Facilitates Membrane Vesiculation through Decreasing Membrane Stiffness

Wang, Hongyin, Lorent, Joseph H., Ganesan, Lakshmi, Diaz-Rohrer, Blanca B., Levental, Kandice R., Malmberg, Eric, Levental, Ilya

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 40 KB

english, 2019

36

Phase Partitioning of Peptide Anchors in Plasma Membrane Vesicles Predicts Their Recruitment to B Cell Receptor Clusters in Live Cells

Shelby, Sarah A., Serrano, Ivan C., Levental, Kandice R., Levental, Ilya, Veatch, Sarah L.

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 63 KB

2019

37

Cell-Derived Plasma Membrane Vesicles Are Permeable to Hydrophilic Macromolecules

Skinkle, Allison D., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 2.98 MB

2020

38

Phospholipid Translocation as Driver of Cholesterol (Re)Distribution

Doktorova, Milka, Symons, Jessica L., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 49 KB

2020

39

Simulations of an Asymmetric Mammalian Lipidome

Doktorova, Milka, Levental, Kandice R., Sezgin, Erdinc, Levental, Ilya, Lyman, Edward R.

Journal:

Biophysical Journal

Year:

2020

Language:

english

File:

PDF, 41 KB

english, 2020

40

Plasma Membrane Packing Asymmetry Drives Transmembrane Protein Localization

Lorent, Joseph H., Ganesan, Lakshmi, Lyman, Edward R., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

Language:

english

File:

PDF, 40 KB

english, 2020

41

Lipid Rafts: Controversies Resolved, Mysteries Remain

Levental, Ilya, Levental, Kandice R., Heberle, Frederick A.

Journal:

Trends in Cell Biology

Year:

2020

Language:

english

File:

PDF, 527 KB

english, 2020

42

Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness

Levental, Kandice R., Malmberg, Eric, Symons, Jessica L., Fan, Yang-Yi, Chapkin, Robert S., Ernst, Robert, Levental, Ilya

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 1.24 MB

english, 2020

43

Myelin-Associated MAL and PLP Are Unusual Among Multi-Pass Transmembrane Proteins in Preferring Ordered Membrane Domains

CASTELLO-SERRANO, IVAN, Lorent, Joseph Helmuth, Ippolito, Rossana, Levental, Kandice R., Levental, Ilya

Journal:

Journal of Physical Chemistry B

Year:

2020

File:

PDF, 2.71 MB

2020

44

Lipidomic atlas of mammalian cell membranes reveals hierarchical variation induced by culture conditions, subcellular membranes, and cell lineages

Symons, Jessica L., Cho, Kwang-Jin, Chang, Jeffrey T., Du, Guangwei, Waxham, M. Neal, Hancock, John F., Levental, Ilya, Levental, Kandice R.

Journal:

Year:

2020

File:

PDF, 3.88 MB

2020

45

Cell-Derived Plasma Membrane Vesicles are Permeable to Hydrophilic Macromolecules

Diaz-Rohrer, Blanca B., Skinkle, Allison, Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 42 KB

2020

46

Homeoviscous Adaptation in Mammalian Cell Membranes in Response to Dietary Lipid Perturbations is Necessary for Cell Survival

Levental, Kandice R., Symons, Jessica L., Fan, Yang-Yi, Chapkin, Robert, Ernst, Robert, Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 44 KB

2020

47

Plasma Membrane Permeability is Altered in Living Mammalian Cells by Perturbations of Lipid Membrane Composition

Symons, Jessica L., Levental, Kandice R., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 40 KB

2020

48

Coupling between Cytoplasmic Protein Phase Separation and Cholesterol-Rich Domains in the Plasma Membrane Facilitates T Cell Activation

Wang, Hongyin, Diaz-Rohrer, Barbara, Levental, Kandice R., Ditlev, Jonathon A., Rosen, Michael K., Levental, Ilya

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 47 KB

2020